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Do you like it here? valacyclovir hcl 500 mg tablet dosage "RE-ALIGN was the first, and remains the only, randomized study performed comparing a new oral anticoagulant with warfarin in patients with mechanical prosthetic heart valves. Our commitment to studying populations with unmet needs, such as those with mechanical prosthetic heart valves, serves to expand the body of knowledge around this novel compound and this patient population," said Sabine Luik, M.D., senior vice president, Medicine & Regulatory Affairs, U.S. Regional Medical Director, Boehringer Ingelheim Pharmaceuticals, Inc. "We are confident in the safety and efficacy of dabigatran when used as directed to reduce the risk of stroke in patients with non-valvular atrial fibrillation. We will continue to study dabigatran in new patient populations in the future."