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propafenone will increase the level or effect of clomipramine by affecting hepatic enzyme CYP2D6 metabolism stromectol 3 mg dosage Anti neoplastic therapies, in particular those that involve cytotoxic agents, are associated with short as well as long term adverse effects 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13